Product name

Anti-c-Myc antibody [Y69] - ChIP Grade
See all c-Myc primary antibodies

Description

Rabbit monoclonal [Y69] to c-Myc - ChIP Grade

Host species

Rabbit

Specificity

This antibody is specific for endogenous c-Myc. It does not detect Myc tag. Expression levels of the target protein vary with sample type and some optimization may be required.

FURTHER INFORMATION ON POSITIVE CONTROLS (Chinese version)

Tested applications

Suitable for: Flow Cyt (Intra), WB, ICC/IF, ChIP-sequencing, IHC-P, IP, ChIC/CUT&RUN-seqmore details

Species reactivity

Reacts with: Mouse, Rat, Human

Immunogen

Synthetic peptide. This information is proprietary to Abcam and/or its suppliers.
(Peptide available as ab166837)

Positive control

• WB: Jurkat, HeLa, HEK-293T, Raji, MCF-7, K562, A20, AR42J, Rat-1, rat pancreas, Neuro-2a cell lysates, L363 MM and CA46 cells. ICC/IF: HEK293 and HeLa cells. IHC-P: Human Burkitt lymphoma, diffuse large B cell lymphoma, adenocarcinoma of the colon, lung adenocarcinoma, gastric adenocarcinoma, urinary bladder transitional carcinoma, esophagus, glioblastoma and low-grade glioma tumor tissues, human skn tissue. IP: Jurkat cell lysate. Flow Cyt (intra), ChIP-seq, ChIC/C&R-seq: HeLa cells, HEK293 cells.

General notes

The proto-oncogene MYC plays a role in human oncogenesis. For more information see here. 

This recombinant rabbit monoclonal antibody (Y69) to c-Myc specifically detects endogenous c-Myc. ab32, the Mouse monoclonal antibody (9E10 clone) to the Myc tag however can be used to study Myc-tagged proteins. More information comparing the two antibodies can be found here.

This product is a recombinant monoclonal antibody, which offers several advantages including:

• - High batch-to-batch consistency and reproducibility
• - Improved sensitivity and specificity
• - Long-term security of supply
• - Animal-free production